1-(2-Hydroxyphenyl)-2-nitroethene

CAS : 3156-43-2

Ref. 3D-FH65831

Informations sur le produit

• Nom: 1-(2-Hydroxyphenyl)-2-nitroethene
• Synonymes: 2'-Hydroxy-beta-Nitrostyrene

Description

1-(2-Hydroxyphenyl)-2-nitroethene is an organocatalytic biomolecule that has been synthesized in an asymmetric fashion. The synthesis of the molecule relies on a squaramide and the use of intramolecular hydrogen transfer reactions to create a nitro group. The molecule was used to generate antiestrogenic activity in MDA-MB-231 breast cancer cells and MCF-7 breast cancer cells by inhibiting estrogen receptor alpha (ERα) transcriptional activity. This molecule has also been shown to be bifunctional, as it inhibits both protein kinase C (PKC) and mitogen-activated protein kinase (MAPK) signaling pathways when applied to these cell lines. X-ray crystal structures of the molecule have been obtained with orientations that exhibit different degrees of hydrophobicity, which may be due to interactions with water molecules.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 165.15 g/mol
• Formule: C₈H₇NO₃
• Degré de pureté: Min. 95%