Informations sur le produit
- (4aR,5R,10bR)-2,3,4,4a,5,6-Hexahydro-12-methyl-1H-5,10b-propeno-1,7-phenanthrolin-8(7H)-one
- (4aR,5S,10bR)-12-methyl-2,3,4,4a,5,6-hexahydro-1H-5,10b-prop[1]eno-1,7-phenanthrolin-8(7H)-one
- 12-Methyl-2,3,4,4a,5,6-hexahydro-1H-5,10b-prop[1]eno-1,7-phenanthrolin-8(7H)-one
- 1H-5,10b-Propeno-1,7-phenanthrolin-8(7H)-one, 2,3,4,4a,5,6-hexahydro-12-methyl-, (4aR,5R,10bR)-
- 1H-5,10b-Propeno-1,7-phenanthrolin-8(7H)-one, 2,3,4,4a,5,6-hexahydro-12-methyl-, [4aR-(4aα,5α,10bα)]-
- 8,15-Didehydro-1,18-dihydro-1-oxolycodine
- Fordimine
- HuperzineB
- Lycodin-1(18H)-one, 8,15-didehydro-
Huperzine B is a natural alkaloid that has been found to have a number of pharmacological effects. It has been shown to inhibit the activity of some enzymes such as phospholipases, cyclooxygenases, and lipoxygenases. Huperzine B also inhibits inflammatory reactions by inhibiting the release of pro-inflammatory cytokines from macrophages and neutrophils. The compound binds to dna duplexes and prevents the DNA from separating. This inhibition causes an increase in intracellular Ca2+ levels, which can lead to cell death by apoptosis or necrosis. Huperzine B is also able to bind iron ions and maintain the homeostasis of this essential metal ion in cells. In addition, huperzine B can decrease bowel disease by reducing inflammation and preventing bacteria from adhering to the intestinal lining.
Huperzine B is used as a preparative hplc for purification of proteins and
