Imperatorin

CAS : 482-44-0

Ref. 3D-FI09972

Informations sur le produit

• Nom: Imperatorin
• Synonymes: 9-[(3-Methyl-2-buten-1-yl)oxy]-7H-furo[3,2-g][1]benzopyran-7-oneAmmidinMarmelosin9-[(3-Methyl-2-buten-1-yl)oxy]-7h-furo[3,2-g][1] benzopyran-7-one, 7H-Furo[3,2-g][1]benzopyran-7-one, 9-[(3-methyl-2-buten-1-yl)oxy]-, 7H-Furo[3,2-g][1]benzopyran-7-one, 9-[(3-methyl-2-butenyl)oxy]-, 8-Isopent-2-enyloxy-6,7-furanocoumarin, 8-Isopentenyloxypsoralene, 9-[(3-Methyl-2-buten-1-yl)oxy]-7H-furo[3,2-g][1]benzopyran-7-one, 9-[(3-methylbut-2-en-1-yl)oxy]-7H-furo[3,2-g]chromen-7-one, Ammidin, Marmelide, Marmelosin, NSC 402949

Description

Imperatorin is a natural compound found in the roots of Angelica Dahurica. It has been shown to have antibacterial efficacy against oral pathogens. Imperatorin inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Imperatorin also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 270.28 g/mol
• Formule: C₁₆H₁₄O₄
• Degré de pureté: Min. 98 Area-%
• Couleur/Forme: White Powder
• InChI: InChI=1S/C16H14O4/c1-10(2)5-7-19-16-14-12(6-8-18-14)9-11-3-4-13(17)20-15(11)16/h3-6,8-9H,7H2,1-2H3
• Code InChI: InChIKey=OLOOJGVNMBJLLR-UHFFFAOYSA-N
• SMILES: CC(C)=CCOc1c2occc2cc2ccc(=O)oc12