Informations sur le produit
- 5-Iodo-2,6-Dioxo-1,2,3,6-Tetrahydropyrimidine-4-Carboxylic Acid
5-Iodoorotic acid is a purine derivative that inhibits the synthesis of proteins in mammalian cells. It forms stable complexes with uridine and sephadex g-100, which can be used to separate and identify uridine. 5-Iodoorotic acid also has an inhibitory effect on the enzyme uridine phosphorylase, which converts uridine into cytosine. This compound has been shown to have a helical structure, and is biosynthesized from tryptophan through a dehydrogenase reaction. 5-Iodoorotic acid is excreted in the urine and plasma concentrations can be monitored by gel chromatography.
5-Iodoorotic acid inhibits protein synthesis by binding to ribonucleic acid (RNA) in the ribosome and preventing peptide bond formation. This causes cell death by inhibiting protein synthesis.
Propriétés chimiques
Question d’ordre technique sur : 3D-FI167403 5-Iodoorotic acid
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