(R)-Irofulven

CAS : 158440-71-2

Ref. 3D-FI24650

Informations sur le produit

• Nom: (R)-Irofulven
• Synonymes: (6'R)-6'-Hydroxy-3'-(hydroxymethyl)-2',4',6'-trimethylspiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one(-)-(Hydroxymethyl)acylfulvene (-)-Irofulven, (-)-(Hydroxymethyl)acylfulvene, (6'R)-6'-hydroxy-3'-(hydroxymethyl)-2',4',6'-trimethylspiro[cyclopropane-1,5'-inden]-7'(6'H)-one, (6′R)-6′-Hydroxy-3′-(hydroxymethyl)-2′,4′,6′-trimethylspiro[cyclopropane-1,5′-[5H]inden]-7′(6′H)-one, 6-Hmaf, Hmaf, Hydroxymethylacylfulvene, Irofulven, Mgi-114, Nsc-683863, Spiro[cyclopropane-1,5′-[5H]inden]-7′(6′H)-one, 6′-hydroxy-3′-(hydroxymethyl)-2′,4′,6′-trimethyl-, (6′R)-, Spiro[cyclopropane-1,5′-[5H]inden]-7′(6′H)-one, 6′-hydroxy-3′-(hydroxymethyl)-2′,4′,6′-trimethyl-, (R)-

Description

(R)-Irofulven is a cytotoxic agent that acts by inhibiting the mitochondrial membrane potential. It has been shown to have high potency against carcinoma cell lines and has been used in toxicity studies. (R)-Irofulven is also effective against high-resistant cells, such as intramolecular hydrogen. This drug induces caspase-independent cell death and chemical stability, which makes it a good candidate for use in children. The concentration-time curve of (R)-Irofulven shows that this drug kills cancer cells at low concentrations and has a long elimination half-life, making it an ideal candidate for cancer treatment.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 246.3 g/mol
• Formule: C₁₅H₁₈O₃
• Degré de pureté: Min. 95%