4-Isopropoxyphenylboronic acid

CAS : 153624-46-5

Ref. 3D-FI38254

Informations sur le produit

• Nom: 4-Isopropoxyphenylboronic acid
• Marque: Biosynth
• Description: 4-Isopropoxyphenylboronic acid is a boronic acid that can be used as a cross-coupling partner in palladium-catalyzed cross-coupling reactions. It is synthesized by reacting 4-hydroxyphenylacetic acid with 2 equivalents of naphthoquinone diazide. The addition of the 4-isopropoxy group to the phenyl substituent increases the reactivity of this boronic acid. This compound has been used in the synthesis of rofecoxib and cyclooxygenase inhibitors, such as aspirin and ibuprofen. The presence of an electron withdrawing group on one phenyl ring enhances the reactivity of this boronic acid towards nucleophiles, such as amines or alcohols.

Propriétés chimiques

• Masse moléculaire: 180.01 g/mol
• Formule: C₉H₁₃BO₃
• Degré de pureté: Min. 95%
• InChI: InChI=1S/C9H13BO3/c1-7(2)13-9-5-3-8(4-6-9)10(11)12/h3-7,11-12H,1-2H3
• Code InChI: InChIKey=CJUHQADBFQRIMC-UHFFFAOYSA-N
• SMILES: CC(C)Oc1ccc(B(O)O)cc1