Lucanthone

CAS : 479-50-5

Ref. 3D-FL161255

Informations sur le produit

• Nom: Lucanthone
• Synonymes: 1-(2-Diethylaminoethylamino)-4-methylthiaxanthen-9-one, 1-[[2-(Diethylamino)ethyl]amino]-4-methyl-9H-thioxanthen-9-one, Lucanthon, Lucatona, NSC 20530, Thioxanthen-9-one, 1-[[2-(diethylamino)ethyl]amino]-4-methyl-, 9H-Thioxanthen-9-one, 1-[[2-(diethylamino)ethyl]amino]-4-methyl-

Description

Lucanthone is an intramolecular hydrogen-transfer compound that is synthesized from the amino acid cysteine. It has been used in biological studies for its ability to inhibit the growth of cancer cells, and may be useful in radiation therapy. Lucanthone has been shown to have a cytotoxic effect on cancer cells by inhibiting cell proliferation and inducing apoptosis. This compound also inhibits autophagy, which is the process of degrading proteins and organelles. Lucanthone has also been shown to decrease cellular viability in wild-type strains of bacteria such as E. coli, but not mutant strains that lack lucanthone reductase activity. This suggests that lucanthone is an inhibitor of physiological function in mammalian tissues, but not bacterial cell functions.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 340.48 g/mol
• Formule: C₂₀H₂₄N₂OS
• Degré de pureté: Min. 95%
• InChI: InChI=1S/C20H24N2OS/c1-4-22(5-2)13-12-21-16-11-10-14(3)20-18(16)19(23)15-8-6-7-9-17(15)24-20/h6-11,21H,4-5,12-13H2,1-3H3
• Code InChI: InChIKey=FBQPGGIHOFZRGH-UHFFFAOYSA-N
• SMILES: CCN(CC)CCNc1ccc(C)c2sc3ccccc3c(=O)c12