(+/-)-Lisofylline

CAS : 6493-06-7

Ref. 3D-FL24910

Informations sur le produit

• Nom: (+/-)-Lisofylline
• Synonymes: 3,7-Dihydro-1-(5-hydroxyhexyl)-3,7-dimethyl-1H-purine-2,6-dione

Description

Lisofylline is a chemical inhibitor of P-glycoprotein (P-gp), which belongs to the group of pharmacological agents. It is used as an active inhibitor in the treatment of bowel disease and is a low potency, non-selective squamous cell nuclear dna (SCCN) p-gp inhibitor. Lisofylline has shown to be an active inhibitor of P-gp in human colon cancer cells. Lisofylline inhibits mitochondrial membrane potential by binding to the rate constant and response element, which prevents ATP production and leads to cell death through oxidative injury.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 280.32 g/mol
• Formule: C₁₃H₂₀N₄O₃
• Degré de pureté: Min. 95%
• InChI: InChI=1S/C13H20N4O3/c1-9(18)6-4-5-7-17-12(19)10-11(14-8-15(10)2)16(3)13(17)20/h8-9,18H,4-7H2,1-3H3
• Code InChI: InChIKey=NSMXQKNUPPXBRG-UHFFFAOYSA-N
• SMILES: CC(O)CCCCn1c(=O)c2c(ncn2C)n(C)c1=O