Lidoflazine

CAS : 3416-26-0

Ref. 3D-FL42905

Informations sur le produit

• Nom: Lidoflazine
• Synonymes: 1-Piperazineacetamide, 4-[4,4-bis(4-fluorophenyl)butyl]-N-(2,6-dimethylphenyl)-, 1-Piperazineaceto-2′,6′-xylidide, 4-[4,4-bis(p-fluorophenyl)butyl]-, 1-[4,4-Bis(4-fluorophenyl)butyl]-4-(2,6-dimethylphenylcarbamoylmethyl)piperazine, 1-[4,4-Bis(fluorophenyl)butyl]-4-(2,6-dimethylanilinocarbonylmethyl)piperazine, 1-[4,4-Di(4-fluorophenyl)butyl]-4-[(2,6-dimethylanilinocarbonyl)methyl]piperazine, 2-{4-[4,4-bis(4-fluorophenyl)butyl]piperazin-1-yl}-N-(2,6-dimethylphenyl)acetamide, 4-[4,4-Bis(4-fluorophenyl)butyl]-N-(2,6-dimethylphenyl)-1-piperazine acetamide, 4-[4,4-Bis(4-fluorophenyl)butyl]-N-(2,6-dimethylphenyl)-1-piperazineacetamide, 4-[4,4-Bis(p-fluorophenyl)butyl]-1-piperazineaceto-2′,6′-xylidide, Alpha-(4-(4,4-Bis(4-Fluorophenyl)Butyl)Piperazin-1-Ylacet)-2,6-Xylidide, Angex, Clinium, Corflazine, Klinium, Lidoflazin, Lidoflazinum, McN-JR 7094, McN-JR 7904, Ordiflazine, R 7904

Description

Lidoflazine is a drug that is used in the treatment of stroke. It has been shown to be effective in reducing brain damage caused by ischemic cerebral injury. Lidoflazine, a benzodiazepine derivative, binds with high affinity to GABA receptors and promotes GABA-mediated chloride ion influx into neurons. This influx leads to an increase in neuronal metabolic rate and the inhibition of oxidative stress-induced neuronal death. The protective effects of Lidoflazine may also be due to its ability to block the synthesis of prostaglandins, which are proinflammatory molecules that play a role in the development of brain damage.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 491.62 g/mol
• Formule: C₃₀H₃₅F₂N₃O
• Degré de pureté: Min. 95%
• InChI: InChI=1S/C30H35F2N3O/c1-22-5-3-6-23(2)30(22)33-29(36)21-35-19-17-34(18-20-35)16-4-7-28(24-8-12-26(31)13-9-24)25-10-14-27(32)15-11-25/h3,5-6,8-15,28H,4,7,16-21H2,1-2H3,(H,33,36)
• Code InChI: InChIKey=ZBIAKUMOEKILTF-UHFFFAOYSA-N
• SMILES: Cc1cccc(C)c1NC(=O)CN1CCN(CCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1