Lubiprostone (ring closed)

CAS : 333963-40-9

Ref. 3D-FL71439

Informations sur le produit

• Nom: Lubiprostone (ring closed)
• Synonymes: (11a)-16,16-Difluoro-11-hydroxy-9,15-dioxo-prostan-1-oic Acid, (11alpha,15R)-16,16-difluoro-15-hydroxy-9-oxo-11,15-epoxyprostan-1-oic acid, (11α,15R)-11,15-Epoxy-16,16-difluoro-15-hydroxy-9-oxoprostan-1-oic acid, (2R,4aR,5R,7aR)-2-(1,1-Difluoropentyl)-2-hydroxy-6-oxo-3,4,4a,5,7,7a-hexahydrocyclopenta[b]pyran-5-heptanoic acid, (8beta,11alpha,15R)-16,16-difluoro-15-hydroxy-9-oxo-11,15-epoxyprostan-1-oic acid, 7-((2R,4aR,5R,7aR)-2-(1,1-Difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl)heptanoic acid, 7-[(1R,3R,6R,7R)-3-(1,1-Difluoropentyl)-3-hydroxy-8-oxo-2-oxabicyclo[4.3.0]non-7-yl]heptanoic acid, 7-[(1R,4R,6R,9R)-4-(1,1-Difluoropentyl)-4-Hydroxy-8-Oxo-5-Oxabicyclo[4.3.0]Non-9-Yl]Heptanoic Acid, 7-[(2R,4aR,5R,7aR)-2-(1,1-difluoropentan-1-yl)-2-hydroxy-6-oxooctahydroxypenta[b]pyran-5-yl]heptanoic acid, Amitiza, Bicyclic lubiprostone, Cyclopenta[b]pyran-5-heptanoic acid, 2-(1,1-difluoropentyl)octahydro-2-hydroxy-6-oxo-, (2R,4aR,5R,7aR)-, Lubiprostone hemiketal, Prostan-1-oic acid, 11,15-epoxy-16,16-difluoro-15-hydroxy-9-oxo-, (11α,15R)-, Ru 0211, Spi 0211, Lubiprostone

Description

Lubiprostone is a glycol ester that increases the frequency and amplitude of spontaneous contractions in the intestine by activating chloride channels in the apical membrane of intestinal cells. Lubiprostone, which is administered by mouth, has been shown to be effective in treating chronic idiopathic constipation. It also has been shown to have beneficial effects on atherosclerotic lesions and bowel disease-related symptoms. Lubiprostone has been evaluated in clinical trials for its treatment of constipation. The drug was found to be safe with few adverse effects and it was also effective in relieving constipation when compared to placebo. Lubiprostone is not recommended for patients with bowel obstruction or ileus because it may worsen these conditions.

Lubiprostone (ring closed) is a medication used for the treatment of chronic idiopathic constipation that belongs to a class of drugs called glycol esters. It works by increasing the frequency and amplitude of spontaneous

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 390.46 g/mol
• Formule: C₂₀H₃₂F₂O₅
• Degré de pureté: Min. 95%