Myelin Proteolipid Protein (139-151) (depalmitoylated) (human, bovine, dog, mouse, rat) trifluoroacetate salt

CAS : 131334-43-5

Ref. 3D-FM109654

Informations sur le produit

• Nom: Myelin Proteolipid Protein (139-151) (depalmitoylated) (human, bovine, dog, mouse, rat) trifluoroacetate salt
• Synonymes: H-His-Cys-Leu-Gly-Lys- Trp-Leu-Gly-His-Pro-Asp-Lys-Phe-OH H-HCLGKWLGHPDKF-OH, Lipophilin (139-151) (Depalmitoylated) (Human, Bovine, Dog, Mouse, Rat), His-Cys-Leu-Gly-Lys-Trp-Leu-Gly-His-Pro-Asp-Lys-Phe, H-His-Cys-Leu-Gly-Lys-Trp-Leu-Gly-His-Pro-Asp-Lys-Phe-Oh (Human, Bovine, Dog, Mouse, Rat), Plp (139-151) (Depalmitoylated) (Human, Bovine, Dog, Mouse, Rat), Myelin Proteolipid Protein (139-151) (Depalmitoylated) (Human, Bovine, Dog, Mouse, Rat)

Description

MPLP(139-151) is a peptide that is derived from the myelin proteolipid protein (PLP). MPLP(139-151) has been shown to inhibit macrophage inflammatory in vitro and brain inflammation in vivo. The inhibition of macrophages was mediated by the induction of apoptosis and inhibition of NF-κB. MPLP(139-151) also induced regression of experimental autoimmune encephalomyelitis in mice, which suggests that it might be useful as a therapeutic agent for multiple sclerosis or other inflammatory diseases.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 1,537.79 g/mol
• Formule: C₇₂H₁₀₄N₂₀O₁₆S
• Degré de pureté: Min. 95%