Methyl pyrazine-2-carboximidoate

CAS : 74617-55-3

Ref. 3D-FM126603

Informations sur le produit

• Nom: Methyl pyrazine-2-carboximidoate
• Synonymes: 2-pyrazinecarboximidic acid, methyl ester, 2-Pyrazinecarboximidic acid, methyl ester

Description

Methyl pyrazine-2-carboximidoate is an anti-tuberculosis drug that belongs to the class of carboximidamides. It has shown tuberculostatic activity in a number of animal models, including guinea pigs and rats infected with Mycobacterium tuberculosis. Methyl pyrazine-2-carboximidoate binds to the mycobacterial cell membrane, resulting in increased permeability and leakage of intracellular material. The drug also has a beneficial effect on the nervous system, as it inhibits imidazoline receptors.
Methyl pyrazine-2-carboximidoate is synthesized from methyl pyrazine-2-carboxylate and 2-(1H)-aminopyridine hydrochloride (1). The carboxylic acid group is converted to an amide by reaction with ammonia in methanol. This amide can be alkylated using methyl iodide

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 137.14 g/mol
• Formule: C₆H₇N₃O
• Degré de pureté: Min. 95%
• InChI: InChI=1S/C6H7N3O/c1-10-6(7)5-4-8-2-3-9-5/h2-4,7H,1H3
• Code InChI: InChIKey=KJPCOZRHGFEIMQ-UHFFFAOYSA-N
• SMILES: COC(=N)c1cnccn1