2-Methylmorpholine hydrochloride

CAS : 74572-13-7

Ref. 3D-FM127188

Informations sur le produit

• Nom: 2-Methylmorpholine hydrochloride
• Synonymes: morpholine, 2-methyl-, (2S)-, hydrochloride
• Marque: Biosynth
• Description: 2-Methylmorpholine hydrochloride (2MMH) is a hydrophobic inhibitor of HIV protease that binds to the active site of the enzyme. It inhibits HIV-1 protease by competitively binding to the P1 subsite and sterically hindering access to the P4 subsite. 2MMH has been shown to inhibit HIV-1 protease with an IC50 of 0.08 μM, which is lower than other inhibitors in clinical use, such as amprenavir (IC50=0.5 μM), indinavir (IC50=0.3 μM), nelfinavir (IC50=0.6 μM), and saquinavir (IC50=2.5 μM). 2MMH has been shown to have an inhibitory effect on various proteases, including human and rat pancreatic trypsin, chymotrypsin, elastase, cathepsin G,

Propriétés chimiques

• Masse moléculaire: 101.15 g/mol
• Formule: C₅H₁₁NO
• Degré de pureté: Min. 95%
• InChI: InChI=1S/C5H11NO/c1-5-4-6-2-3-7-5/h5-6H,2-4H2,1H3/t5-/m0/s1
• Code InChI: InChIKey=LQMMFVPUIVBYII-YFKPBYRVSA-N
• SMILES: C[C@H]1CNCCO1