2-Methyl-5-nitrobenzenesulfonamide

CAS : 6269-91-6

Ref. 3D-FM143864

Informations sur le produit

• Nom: 2-Methyl-5-nitrobenzenesulfonamide
• Synonymes: 2-Methyl-5-nitrobenzenesulphonamide, 2-Methyl-5-Nitrobenzene-1-Sulfonamide, 2-Methyl-5-nitrobenzene sulphonamide

Description

2-Methyl-5-nitrobenzenesulfonamide is a synthetic nitrosated hydroxamic acid that inhibits the histone deacetylase enzyme. This leads to an increase in gene transcription and protein synthesis. 2-Methyl-5-nitrobenzenesulfonamide has been shown to be highly potent against various cancer cell lines, including breast, ovarian, and prostate cancers. It is also used as a lead compound in the development of pazopanib, which is a drug for the treatment of advanced renal cell carcinoma. Pazopanib is metabolized by CYP3A4 enzymes to form 2-methyl-5-nitrobenzenesulfonamide. The impurities found in this drug are not toxic and do not contribute to its antitumor activity.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 216.22 g/mol
• Formule: C₇H₈N₂O₄S
• Degré de pureté: Min. 95%