(2S,3S)-3-Methylpyrrolidine-2-carboxylicacid
CAS : 10512-89-7
Ref. 3D-FM148365
Taille indéfinie | À demander |
Informations sur le produit
- D-3-Methylproline
- 3-Methyl-L-Proline
- Trans-3-Methyl-L-Proline
- (3S)-3-methyl-L-proline
(2S,3S)-3-Methylpyrrolidine-2-carboxylic acid (PMPCA) is a natural product that inhibits the enzyme catalysis of the bacterial GTPase-activating protein (GAP). It is a homochiral compound, which means that it can be synthesized from a single chiral starting material. PMPCA has shown antibiotic activity against gram-positive bacteria, such as Staphylococcus aureus and Streptococcus pneumoniae. This compound has been found to inhibit the synthesis of proteins in these bacteria by inhibiting the action of hydroxylase and x-ray crystal structures have been determined for this compound. The biosynthesis pathway for PMPCA has also been discovered and studied in detail using liquid chromatography methods.
Propriétés chimiques
Question d’ordre technique sur : 3D-FM148365 (2S,3S)-3-Methylpyrrolidine-2-carboxylicacid
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