Informations sur le produit
Nom :
R-(-)-Manidipine
Synonymes :
- (4R)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-[4-(diphenylmethyl)-1-piperazinyl]ethyl methyl ester (-)-Manidipine
- (-)-Manidipine
- (4R)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 2-[4-(Diphenylmethyl)-1-piperazinyl]ethyl Methyl Ester
- 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[4-(diphenylmethyl)-1-piperazinyl]ethyl methyl ester, (4R)-
- 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[4-(diphenylmethyl)-1-piperazinyl]ethyl methyl ester, (4R)- (9CI)
- 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[4-(diphenylmethyl)-1-piperazinyl]ethyl methyl ester, (R)-
- O3-[2-(4-benzhydrylpiperazin-1-yl)ethyl] O5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Description :
R-(-)-Manidipine is a chiral compound that is metabolized in the body to form two enantiomers, (+)- and (-)-manidipine. The pharmacokinetic study of R-(-)-Manidipine was conducted by comparing the plasma concentrations of the racemic mixture with those of the individual enantiomers. The diastereomeric ratios were determined by analyzing plasma samples using a mass spectrometer and reaction monitoring. The pharmacokinetic study showed that both enantiomers have antihypertensive activity, but (-)-manidipine has higher potency than (+)-manidipine.
Avis:
Nos produits sont destinés uniquement à un usage en laboratoire. Pour tout autre usage, veuillez nous contacter.
Marque:
Biosynth
Stockage à long terme :
Notes :
Propriétés chimiques
Masse moléculaire :
610.7 g/mol
Formule :
C35H38N4O6
Degré de pureté :
Min. 95%
MDL:
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