N-Methyl picolinamide

CAS : 6144-78-1

Ref. 3D-FM25544

Informations sur le produit

• Nom: N-Methyl picolinamide
• Synonymes: N-Methyl-2-pyridinecarboxamideN-Methylpicolinamide
• Marque: Biosynth
• Description: N-Methyl picolinamide is a novel anticancer agent that inhibits the activity of BCR-ABL kinase. It has been shown to be effective against human colon cancer cells (HCT116) and breast cancer cells (MCF-7). N-Methyl picolinamide binds to the ATP binding site of BCR-ABL kinase, inhibiting its enzymatic activity. The compound also binds to annexin II and blocks cell cycle progression at G2/M phase. The chemical structure of N-Methyl picolinamide includes an amide group, which may lead to low bioavailability. This drug has significant inhibitory activities against nitrogen atoms and inhibition constants for both the A and B forms of the enzyme.

Propriétés chimiques

• Masse moléculaire: 136.15 g/mol
• Formule: C₇H₈N₂O
• Degré de pureté: Min. 95%
• Couleur/Forme: Colorless Powder
• InChI: InChI=1S/C7H8N2O/c1-8-7(10)6-4-2-3-5-9-6/h2-5H,1H3,(H,8,10)
• Code InChI: InChIKey=HXXAUIXTYRHFNO-UHFFFAOYSA-N
• SMILES: CNC(=O)c1ccccn1