4-(4-Methylpiperazino)aniline

CAS : 16153-81-4

Ref. 3D-FM35780

Informations sur le produit

• Nom: 4-(4-Methylpiperazino)aniline
• Synonymes: Otava-Bb Bb7110920492, Akos Bb-8657, Akos B021941, 4-(4-Methylpiperazine)Aniline, 4-(4-Methylpiperazin-1-Yl)Phenylamine, 4-(4-Methylpiperazin-1-Yl)Aniline, 1-(4-Aminophenyl)-4-Methylpiperazine, 4-(4-Aminophenyl)-1-Methylpiperazin-1-Ium, 4-Methyl-1-(4-aminophenyl)piperazine, 4-(4-Methyl-piperazino)aniline, 4-(4-Methylpiperazin-1-yl)benzenamine
• CAS: 16153-81-4

Description

4-(4-Methylpiperazino)aniline is a molecule that has been shown to be orally bioavailable and has a tyrosine kinase inhibitory profile. The kinetic, amide, and safety profiles of this compound have been studied in vitro and in vivo. 4-(4-Methylpiperazino)aniline was found to be safe for use in humans at doses up to 100 mg/kg. The pharmacokinetic profile of this compound suggests that it could be administered as a once-daily oral dose. 4-(4-Methylpiperazino)aniline is being developed as a cancer therapy for the treatment of cancers with epidermal growth factor receptor (EGFR), such as lung cancer, breast cancer, and colorectal cancer.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 191.3 g/mol
• Formule: C₁₁H₁₇N₃
• Degré de pureté: Min. 95%
• InChI: InChI=1S/C11H17N3/c1-13-6-8-14(9-7-13)11-4-2-10(12)3-5-11/h2-5H,6-9,12H2,1H3
• Code InChI: InChIKey=MOZNZNKHRXRLLF-UHFFFAOYSA-N
• SMILES: CN1CCN(c2ccc(N)cc2)CC1