3-Methylbenzenesulfonyl chloride

CAS : 1899-93-0

Ref. 3D-FM59089

Informations sur le produit

• Nom: 3-Methylbenzenesulfonyl chloride
• Synonymes: 3-Toluenesulfonyl chloride, M-toluenesulfonyl chloride, 3-Methylbenzenesulfonyl Chloride, m-Toluenesulphonyl chloride

Description

3-Methylbenzenesulfonyl chloride is a synthetic compound that is a potent 5-HT7 receptor agonist. It has been shown to stimulate locomotor activity and induce convulsions in mice. 3-Methylbenzenesulfonyl chloride was found to have a high safety profile in preclinical studies and did not show any signs of neurotoxicity. The molecule also has functional effects on the 5-HT7 receptor, including partial agonism, antagonism, and inverse agonism. 3-Methylbenzenesulfonyl chloride binds to the pyrazole ring of the 5-HT7 receptor by ring opening or hydrogen bonding with an amide nitrogen atom in its peptidomimetic form. This binding induces conformational changes in the 5-HT7 receptor that lead to G protein activation and downstream signaling pathways that result in antiproliferative effects.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 190.65 g/mol
• Formule: C₇H₇SO₂Cl
• Degré de pureté: Min. 95%
• Couleur/Forme: Clear Liquid
• InChI: InChI=1S/C7H7ClO2S/c1-6-3-2-4-7(5-6)11(8,9)10/h2-5H,1H3
• Code InChI: InChIKey=KFPMLWUKHQMEBU-UHFFFAOYSA-N
• SMILES: Cc1cccc(S(=O)(=O)Cl)c1