1-Isobutyl-1H-benzimidazole

CAS : 305346-88-7

Ref. 3D-FMA34688

Informations sur le produit

• Nom: 1-Isobutyl-1H-benzimidazole
• Synonymes: 1-(2-Methylpropyl)-1H-1,3-benzodiazole, 1-(2-Methylpropyl)-1H-benzimidazole, 1-Isobutylbenzimidazole, 1H-Benzimidazole,1-(2-methylpropyl)-(9CI), 1H-Benzimidazole, 1-(2-methylpropyl)-

Description

1-Isobutyl-1H-benzimidazole is a potent and selective inhibitor of cell proliferation. It inhibits the growth of cancer cells by targeting the catalytic activity of topoisomerase II. The in vitro cytotoxic activity of 1-isobutyl-1H-benzimidazole has been investigated on human cancer cells and endometrial cancer cells. The IC50 values for cisplatin, a chemotherapeutic agent, and 1-isobutyl-1H-benzimidazole were found to be identical at 10 μM. Endometrial cancer cells were more sensitive to 1-isobutyl-1H-benzimidazole than human cancer cells.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 174.24 g/mol
• Formule: C₁₁H₁₄N₂
• Degré de pureté: Min. 95%