5-Nitroisophthalic acid monomethyl ester

CAS : 1955-46-0

Ref. 3D-FN137812

Informations sur le produit

• Nom: 5-Nitroisophthalic acid monomethyl ester
• Synonymes: Mono-methyl 5-nitroisophthalate, 1,3-Benzenedicarboxylic acid, 5-nitro-, 1-methyl ester, 1,3-Benzenedicarboxylic acid, 5-nitro-, monomethyl ester, 1-Methyl 5-nitro-1,3-benzenedicarboxylate, 3-(Methoxycarbonyl)-5-Nitrobenzoate, 3-(Methoxycarbonyl)-5-Nitrobenzoic Acid, 3-Carbomethoxy-5-nitrobenzoic acid, 3-Nitro-5-(methoxycarbonyl)benzoic acid, 5-Nitro Isophthalic Acid Monomethyl Ester, 5-Nitro-1,3-benzenedicarboxylic acid methyl ester, 5-Nitro-1,3-benzenedicarboxylic acid monomethyl ester, 5-Nitro-3-(carbomethoxy)benzoic acid, 5-Nitroisophthalic acid methyl ester, Isophthalic acid, 5-nitro-, methyl ester, Isophthalic acid, 5-nitro-, monomethyl ester, Methyl 3-carboxy-5-nitrobenzoate, Methyl 5-Nitroisophthalate, Methyl hydrogen 5-nitroisophthalate, Monomethyl 5-nitrobenzene-1,3-dicarboxylate, mono-Methyl 5-nitroisophthalate

Description

5-Nitroisophthalic acid monomethyl ester (NIAE) is an acetylating agent that can be used for the preparation of 5-nitroisophthalic acid, which is a precursor to the synthesis of dyes and pharmaceuticals. The acetylation reaction of NIAE with proteins produces an insensitive material. Acetylation also inhibits the activity of serine proteases and virus replication. In addition, it has been found that the catalytic reduction of NIAE with palladium is faster than other synthetic methods. Optimal reaction conditions are obtained by adding chloride ions to the reaction mixture, while reductive conditions are optimal for catalysis. Reaction time can be shortened by using a soluble catalyst such as iodide ion or mercury(II) sulfate. The active site of NIAE contains a nitro group that reacts with substrates in the presence of oxygen, forming a product from which the acetyl group has been removed

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 225.16 g/mol
• Formule: C₉H₇NO₆
• Degré de pureté: Min 98%
• Couleur/Forme: Powder