Nicorandil

CAS : 65141-46-0

Ref. 3D-FN15906

Informations sur le produit

• Nom: Nicorandil
• Synonymes: 2-(Pyridine-3-carboxamido)ethyl NitrateN-[2-(Nitrooxy)ethyl]pyridine-3-carboxamide, 2-(Pyridine-3-carbonylamino)ethyl nitrate, 2-Nicotinamidoethyl nitrate, 2-[(3-Pyridinylcarbonyl)amino]ethyl nitrate, 2-[(Pyridin-3-yl)formamido]ethyl nitrate, 2-[(Pyridin-3-ylcarbonyl)amino]ethyl nitrate, 2-[(Pyridin-3-ylcarbonyl)amino]ethylnitrat, 265-514-1, 3-Pyridinecarboxamide, N-[2-(nitrooxy)ethyl]-, Coronel, Dancor, Ikorel, N-(2-Hydroxyethyl)nicotinamide nitrate, N-(2-Hydroxyethyl)nicotinamide nitrate ester, N-(2-Nitrooxyethyl)nicotinamide, N-[2-(Nitrooxy)ethyl]-3-pyridinecarboxamide, Perisalol, Sg 75, Sigmart, U 64417

Description

Nicorandil is an ATP-dependent potassium channel activator. It activates mitochondrial ATP-dependent potassium (KATP) channels and inhibits the TLR4/MyD88/NF-κB/NLRP3 pathway, which reduces myocardial infarction-induced pyroptosis. Pyroptosis is an inflammatory cell death process that regulates cardiomyocyte loss after myocardial infarction. These findings suggest that nicorandil may be a potential therapy for ischemic heart disease due to its cardioprotective effects.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 211.17 g/mol
• Formule: C₈H₉N₃O₄
• Degré de pureté: Min. 95%
• Couleur/Forme: White Powder