N-(2-phosphonoacetyl)-L-aspartic acid sodium

CAS : 51321-79-0

Ref. 3D-FN177555

Informations sur le produit

• Nom: N-(2-phosphonoacetyl)-L-aspartic acid sodium
• Synonymes: (2S)-2-(2-Phosphonoacetamido)butanedioic acid, (2S)-2-[(2-Phosphonoacetyl)amino]butanedioic acid, <span class="text-smallcaps">L</span>-Aspartic acid, N-(2-phosphonoacetyl)-, <span class="text-smallcaps">L</span>-Aspartic acid, N-(phosphonoacetyl)-, Acide sparfosique, Acide sparfosique [INN-French], Acido sparfosico, Acido sparfosico [INN-Spanish], Acidum sparfosicum, Acidum sparfosicum [INN-Latin], L-Aspartic acid, N-(phosphonoacetyl)-, N-(2-Phosphonoacetyl)-<span class="text-smallcaps">L</span>-aspartic acid, N-(Phosphonacetyl)-L-aspartic acid, N-(Phosphonoacetyl)-<span class="text-smallcaps">L</span>-aspartic acid, N-(Phosphonoacetyl)-L-aspartic acid, N-(Phosphonoacetyl)-asparaginsaeure, N-(phosphonoacetyl)aspartic acid, N-Phosphonacetyl-<span class="text-smallcaps">L</span>-aspartic acid, N-Phosphonacetyl-L-aspartate, Nci 224131, Nsc 224131, Pala, Phosphonoacetyl-<span class="text-smallcaps">L</span>-aspartic acid, Sparfosic Acid, Sparfosic Acid [INN], Unii-78Qvz7Rg8L, tetrasodium (2S)-2-[(phosphonatoacetyl)amino]butanedioate

Description

N-(2-phosphonoacetyl)-L-aspartic acid sodium (NPA) is a prodrug that is hydrolyzed to L-aspartic acid in vivo. It has been shown to inhibit the enzyme activity of peptide hormones, such as insulin and glucagon. In addition, NPA inhibits x-ray diffraction data of uridine and hl-60 cells. NPA also inhibits the activity of enzymes that are involved in cancer therapy, such as esterase and phosphatase. This drug may be useful for chemotherapeutic treatment because it has minimal toxicity even at high doses and resistant mutants cannot develop against it.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 255.12 g/mol
• Formule: C₆H₁₀NO₈P•Nax
• Degré de pureté: Min. 95%