(R)-(-)-nipecotic acid
CAS : 25137-00-2
Ref. 3D-FN55407
2g | À demander | |
5g | À demander | |
10g | À demander | |
25g | À demander | |
50g | À demander |
Informations sur le produit
- (R)-()-3-Piperidinecarboxylic acid
- (-)-Nipecotic acid
- (3R)-3-Piperidinecarboxylic acid
- (3R)-Piperidine-3-carboxylic acid
- (3R)-piperidinium-3-carboxylate
- (3S)-piperidinium-3-carboxylate
- (R)-3-Piperidinecarboxylic acid
- 3-Piperidinecarboxylic acid, (3R)-
- 3-Piperidinecarboxylic acid, (R)-
- <span class="text-smallcaps">L</span>-(-)-Nipecotic acid
- Voir d'autres synonymes
- D-Piperidine-3-carboxylic acid
- Nipecotic acid, (R)-(-)-
- R-(-)-Piperidine-3-carboxylic acid
(R)-(-)-Nipecotic acid is a non-competitive inhibitor of gamma-aminobutyric acid (GABA) uptake. It is also a cholinergic antagonist and an inhibitor of GABA uptake in vitro. Nipecotic acid has been shown to have anticonvulsant effects in animal models and to be effective in the treatment of alcohol withdrawal syndrome. Nipecotic acid has been shown to protect against seizures induced by potassium chloride, pentylenetetrazole, or glutamate in rat brain slices as well as by electroconvulsive shock. It also prevents convulsions induced by pentylenetetrazole or kainic acid when applied locally on the cerebral cortex. The mechanism for this effect may be due to inhibition of GABA uptake by nipecotic acid or an increase in the release of GABA from nerve endings.
Propriétés chimiques
Question d’ordre technique sur : 3D-FN55407 (R)-(-)-nipecotic acid
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