Ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate

CAS : 330785-81-4

Ref. 3D-FNA78581

Informations sur le produit

• Nom: Ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate
• Synonymes: 4-(3-Chloro-4-Methoxy-Benzylamino) -2-Methylsulfanyl-Pyrimidine- 5-Carboxylic Acid Ethyl Ester, 4-(3-Chloro-4-methoxybenzylamino)-5-ethoxycarbonyl-2-methylthiopyrimidine, 4-[[(3-Chloro-4-methoxyphenyl)methyl]amino]-2-(methylthio)-5-pyrimidinecarboxylic acid ethyl ester, 5-Pyrimidinecarboxylic acid, 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-2-(methylthio)-, ethyl ester, Ethyl 4-(3-Chloro-4-Methoxybenzylamino)-2-(Methylthio)Pyrimidine-5-Carboxylate, Ethyl 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-2-(methylthio)-5-pyrimidinecarboxylate

Description

Ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate is an intermediate in the synthesis of avanafil. It is a precursor to the drug avanafil, which is used as a treatment for erectile dysfunction. This compound undergoes hydrolysis and condensation reactions to form a product with a reaction yield of 89%. The reaction proceeds sequentially by first forming an acetic acid ester, then adding ethyl bromoacetate, and finally hydrolyzing the ester.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 367.86 g/mol
• Formule: C₁₆H₁₈ClN₃O₃S
• Degré de pureté: Min. 95%
• Couleur/Forme: Powder