Informations sur le produit
Nom :
OSU-03012
Synonymes :
- 2-Amino-N-[4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]acetamide
- 2-Amino-N-[4-[5-phenanthren-2-yl-3-(trifluoromethyl)pyrazol-1-yl]phenyl]acetamide
- AR 12 (pharmaceutical)
- Acetamide, 2-amino-N-[4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-
- Ar-12
- Osu-03012
Description :
OSU-03012 is an antibiotic that belongs to the group of beta-lactam antibiotics. It has shown potent activity against antibiotic-resistant strains, including methicillin-resistant Staphylococcus aureus isolates and Mycobacterium tuberculosis. OSU-03012 binds to the response element on the surface of cells, blocking viral replication. OSU-03012 inhibits the polymerase chain reaction by binding to DNA polymerase at the active site and preventing formation of an RNA primer. This drug also activates apoptosis by inhibiting mitochondrial membrane potential and autophagy pathways in cancer cells, which may be due to its ability to bind to Mcl-1 protein.
Avis:
Nos produits sont destinés uniquement à un usage en laboratoire. Pour tout autre usage, veuillez nous contacter.
Marque:
Biosynth
Stockage à long terme :
Notes :
Propriétés chimiques
Masse moléculaire :
460.45 g/mol
Formule :
C26H19F3N4O
Degré de pureté :
Min. 95%
InChI :
InChI=1S/C26H19F3N4O/c27-26(28,29)24-14-23(33(32-24)20-10-8-19(9-11-20)31-25(34)15-30)18-7-12-22-17(13-18)6-5-16-3-1-2-4-21(16)22/h1-14H,15,30H2,(H,31,34)
Code InChI :
InChIKey=YULUCECVQOCQFQ-UHFFFAOYSA-N
SMILES :
NCC(=O)Nc1ccc(-n2nc(C(F)(F)F)cc2-c2ccc3c(ccc4ccccc43)c2)cc1
MDL:
Point de fusion :
Point d'ébullition :
Point d'éclair :
Densité :
Concentration :
EINECS :
Merck :
Code SH :
