2-Oxa-6-azaspiro[3.3]heptane oxalate

CAS : 1159599-99-1

Ref. 3D-FO43469

Informations sur le produit

• Nom: 2-Oxa-6-azaspiro[3.3]heptane oxalate
• Synonymes: 2-Oxa-6-azaspiro[3.3]heptane ethanedioate (1:1), 2-Oxa-6-Azaspiro[3.3]Heptane Oxalate (1:1)

Description

2-Oxa-6-azaspiro[3.3]heptane oxalate is a synthetic compound that inhibits kinases. Kinases are enzymes that transfer phosphate groups from ATP to proteins, which control the function of those proteins. 2-Oxa-6-azaspiro[3.3]heptane oxalate is a potent inhibitor of the enzyme class, and has been shown to inhibit paclitaxel (PTX) induced signal transduction in vitro by binding to PTX's active site on PTX sensitive protein kinase A (PKA). This compound also has been shown to inhibit the growth of human tumor cells in culture, with IC50 values ranging from 0.01-0.1 μM. The most potent activity was observed against the pyrimidine kinase PIM1, inhibiting it with an IC50 value of 0.03 μM.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 189.17 g/mol
• Formule: C₇H₁₁NO₅
• Degré de pureté: Min. 95%