2-Oxoindoline-6-carboxylic acid

CAS : 334952-09-9

Ref. 3D-FO75052

Informations sur le produit

• Nom: 2-Oxoindoline-6-carboxylic acid
• Synonymes: 6-Carboxyoxindole2-Oxo-2,3-dihydro-1H-indole-6-carboxylic acid, 1H-Indole-6-carboxylic acid, 2,3-dihydro-2-oxo-

Description

2-Oxoindoline-6-carboxylic acid is a chemical intermediate that can be used to synthesize the anticancer agent nintedanib. This compound is a phenyl, dimethylamino, trimethyl, and intermediates. It has been shown to have an inhibitory effect on DNA synthesis in cancer cells by blocking the activity of DNA polymerase and ribonucleotide reductase. 2-Oxoindoline-6-carboxylic acid also has an anti-inflammatory effect by inhibiting prostaglandin synthesis and suppressing the production of inflammatory cytokines such as IL1β and IL8.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 177.16 g/mol
• Formule: C₉H₇NO₃
• Degré de pureté: Min. 95%
• InChI: InChI=1S/C9H7NO3/c11-8-4-5-1-2-6(9(12)13)3-7(5)10-8/h1-3H,4H2,(H,10,11)(H,12,13)
• Code InChI: InChIKey=IIKVTJWRBSYRSA-UHFFFAOYSA-N
• SMILES: O=C1Cc2ccc(C(=O)O)cc2N1