PAR-2 (1-6) (human) trifluoroacetate salt

CAS : 202933-49-1

Ref. 3D-FP109441

Informations sur le produit

• Nom: PAR-2 (1-6) (human) trifluoroacetate salt
• Synonymes: H-Ser-Leu-Ile-Gly-Lys-Val-OH H-SLIGKV-OH
• Marque: Biosynth
• Description: PAR-2 is a cytosolic protein that is activated by calcium. PAR-2 activation induces the synthesis of prostaglandins and other inflammatory mediators, which stimulate the release of substances from cells such as cytokines and chemokines. PAR-2 also has an important role in cell proliferation, differentiation, apoptosis, and cancer development. PAR-2 activation is induced by proteases such as trypsin or soybean trypsin inhibitor. The trifluoroacetate salt form of PAR-2 (1-6) has been used to inhibit protease activity in colon cancer cells and prostate cancer cells.; PAR-2 (1-6) (human) trifluoroacetate salt H-Ser-Leu-Ile-Gly-Lys-Val-OH trifluoroacetate salt is a potent chemical inhibitor of trypsin activity with IC50 values of 0.5 µM for soybean trypsin inhibitor

Propriétés chimiques

• Masse moléculaire: 615.76 g/mol
• Formule: C₂₈H₅₃N₇O₈
• Degré de pureté: Min. 95%