2,4-Pyrimidinediamine, 6-ethyl-
CAS : 514854-12-7
Ref. 3D-FP153961
| 1g | Arrêté | ||
| 50mg | Arrêté | ||
| 100mg | Arrêté | ||
| 250mg | Arrêté | ||
| 500mg | Arrêté |
Informations sur le produit
Nom :
2,4-Pyrimidinediamine, 6-ethyl-
Synonymes :
- 6-Ethyl-pyrimidine-2,4-diyldiamine
- 2,4-Pyrimidinediamine, 6-ethyl- (9CI)
- 6-Ethyl-2,4-Pyrimidinediamine
- 2,4-Diamino-6-ethylpyrimidine
- 6-Ethylpyrimidine-2,4-Diamine
Description :
2,4-Pyrimidinediamine, 6-ethyl is a molecule that has been shown to have antimalarial activity in experimental studies. It is a selective inhibitor of the parasite Plasmodium falciparum. This drug inhibits the synthesis of pyrimethamine and its metabolites by targeting the enzyme dihydrofolate reductase, which is required for the synthesis of purines and pyrimidines. 2,4-Pyrimidinediamine, 6-ethyl has been found to be cytotoxic against human tumor cell lines at concentrations of 10 μM but not against nonmalignant cells. The molecular modeling study suggests that this drug binds to a groove on the surface of the protein and blocks access to an important site for binding with other molecules.
Avis:
Nos produits sont destinés uniquement à un usage en laboratoire. Pour tout autre usage, veuillez nous contacter.
Marque:
Biosynth
Stockage à long terme :
Notes :
Propriétés chimiques
Masse moléculaire :
138.17 g/mol
Formule :
C6H10N4
Degré de pureté :
Min. 95%
InChI :
InChI=1S/C6H10N4/c1-2-4-3-5(7)10-6(8)9-4/h3H,2H2,1H3,(H4,7,8,9,10)
Code InChI :
InChIKey=FVSSMWRJBRKTOY-UHFFFAOYSA-N
SMILES :
CCc1cc(N)nc(N)n1
MDL:
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Code SH :
