Pyrazine-2-carboxylic acid

CAS : 98-97-5

Ref. 3D-FP15650

Informations sur le produit

• Nom: Pyrazine-2-carboxylic acid
• Synonymes: 1,4-Diazinecarboxylic acid, 2-Carboxyl-pyrazine, 2-Carboxypyrazine, 2-Pyrazinecarboxylic, 2-Pyrazinoic acid, Acide Pyrazine-2-Carboxylique, Acido Pirazina-2-Carboxilico, Nsc 13146, Nsc 27192, Paradiazinecarboxylic acid, Pyrazin-2-carbonsaure, Pyrazine-2-formic acid, Pyrazinecarboxylic acid, Pyrazinic acid, Pyrazinoic acid, Rarechem Al Bo 0493, Timtec-Bb Sbb000051

Description

Pyrazine-2-carboxylic acid is a potent inhibitor of bacterial x-lactamase. It was found that the inhibition of x-lactamase by pyrazine-2-carboxylic acid could be attributed to hydrogen bonding interactions with the active site of the enzyme and a high rate constant for the reaction. The antibacterial efficacy of pyrazine-2-carboxylic acid against wild type Streptococcus pneumoniae and methicillin resistant Staphylococcus aureus (MRSA) was tested and found to be comparable to that of benzylpenicillin. Pyrazine-2-carboxylic acid also has biological properties, such as an inhibitory effect on protein synthesis in bacteria, which may be due to its ability to bind to ribosomes.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 124.1 g/mol
• Formule: C₅H₄N₂O₂
• Degré de pureté: Min. 95%
• Couleur/Forme: Powder