DL-a-Phenylglycine

CAS : 2835-06-5

Ref. 3D-FP40116

Informations sur le produit

• Nom: DL-a-Phenylglycine
• Synonymes: (+/-)-alpha-Aminophenylacetic acid, (.+-.)-Phenylglycine, (.+-.)-α-Phenylglycine, (2S)-amino(phenyl)ethanoic acid, (Phenylamino)Acetate, (RS)-2-Phenylglycine, 2-Amino-2-phenylacetic acid, 2-Amino-2-phenylethanoic acid, 2-Phenylglycine, <span class="text-smallcaps">DL</span>-2-Phenylglycine, <span class="text-smallcaps">DL</span>-Phenylglycine, <span class="text-smallcaps">DL</span>-α-Aminophenylacetic acid, <span class="text-smallcaps">DL</span>-α-Phenylglycine, Anilinoacetic acid, Benzeneacetic acid, α-amino-, C-Phenylglycine, DL-2-Phenylglycine, DL-Phenylglycine, DL-alpha-Aminophenylacetic acid, DL-α- PHENYLGLYCINE, DL-α-Aminophenylacetic acid, DL-α-Phenylglycin, DL-α-fenilglicina, Glycine, 2-phenyl-, <span class="text-smallcaps">DL</span>-, Glycine, 2-phenyl-, DL-, H-DL-Phg-OH, N-Pgc, N-Phenylglycine, Nsc 24619, Nsc 32070, Nsc 7928, Phenylacetic Acid, Dl-A-Amino-, Potassium (Phenylamino)Acetate, RS-2-Aminobenzeneacetic Acid, Rs-Aminobenzeneacetic Acid, α-Aminobenzeneacetic acid, α-Aminophenylacetic acid

Description

DL-a-phenylglycine is a natural compound that has been identified as a selective inhibitor of cyclooxygenase 2 (COX-2), and it exhibits antiinflammatory activity. DL-a-phenylglycine has been shown to inhibit COX-2 at low concentrations and to be less potent than aspirin in inhibiting COX-1. DL-a-phenylglycine is also an amide, with a molecular weight of 296. In order to determine the structure of DL-a-phenylglycine, XRD data was collected from the monosodium salt form of the compound. The ester hydrochloride form was used for enzyme activity assays because it is more soluble in water than the free base form. The synthesis of DL-a-phenylglycine was achieved through a two step process involving amide formation and hydrolysis.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 151.16 g/mol
• Formule: C₈H₉NO₂
• Degré de pureté: Min. 95%
• Couleur/Forme: Solid
• InChI: InChI=1S/C8H9NO2/c9-7(8(10)11)6-4-2-1-3-5-6/h1-5,7H,9H2,(H,10,11)
• Code InChI: InChIKey=ZGUNAGUHMKGQNY-UHFFFAOYSA-N
• SMILES: NC(C(=O)O)c1ccccc1