Informations sur le produit
- 9-(1-Propen-1-yl)-9H-purin-6-amine
- 9H-Purin-6-amine, 9-(1-propen-1-yl)-
- Adenine, 9-propenyl-
- Tenofovir Disoproxil Related Compound B (10 mg) ((E)-9-(Prop-1-enyl)-9H-purin-6-amine)
9-Propenyladenine is a natural product that is an extractant and organic solvent. It has been shown to have protein synthesis inhibition activity against the ribosomal subunit. 9-Propenyladenine also inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. 9-Propenyladenine also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.