Informations sur le produit
- Acetic acid, 2,2,2-trifluoro-, phenyl ester
- Acetic acid, trifluoro-, phenyl ester
- Phenyl 2,2,2-trifluoroacetate
- Phenyl trifluoroacetate
Phenyl trifluoroacetate is a chemical compound that undergoes an acylation reaction with alcohols to produce esters. It is used in the synthesis of HIV protease inhibitor drugs such as amprenavir, atazanavir, and lopinavir. Phenyl trifluoroacetate has been shown to be a potent inhibitor of HIV-1 protease due to its reactivity with the hydroxyl group in the enzyme's active site. The kinetic and reaction mechanism for phenyl trifluoroacetate are not well understood because it has not been possible to determine the structure of the drug. This compound is also used as a cross-linking agent in biopolymer research and as a molecule for organic synthesis.