rac cotinine

CAS : 15569-85-4

Ref. 3D-FR27494

Informations sur le produit

• Nom: rac cotinine
• Synonymes: 1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone(+/-)-Cotinine, 2-Pyrrolidinone, 1-methyl-5-(3-pyridinyl)-, 1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone, 1-Methyl-5-(Pyridin-3-Yl)Pyrrolidin-2-One
• CAS: 15569-85-4

Description

Rac-cotinine is a human metabolite of cotinine. It has been found to be a 5-HT4 receptor agonist, which may contribute to its psychoactive effects. Rac-cotinine has been shown to have antidepressant properties in humans by inhibiting the reuptake of serotonin, norepinephrine, and dopamine. Rac-cotinine also inhibits the production of nitric oxide (NO) in the liver and is an analytical method for detecting cotinine in human plasma samples. The chemical reaction mechanism for rac-cotinine involves the formation of methyl ketones through a two-step process that begins with enzymatic hydrolysis of nicotine. In vitro studies have shown that rac-cotinine is synthesized from nicotine by lipase and monoamine oxidase (MAO). Rac-cotinine can then be converted into other metabolites, such as cotinine and anabasine, through methylation reactions catalyzed by S

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 176.22 g/mol
• Formule: C₁₀H₁₂N₂O
• Degré de pureté: Min. 95%
• InChI: InChI=1S/C10H12N2O/c1-12-9(4-5-10(12)13)8-3-2-6-11-7-8/h2-3,6-7,9H,4-5H2,1H3
• Code InChI: InChIKey=UIKROCXWUNQSPJ-UHFFFAOYSA-N
• SMILES: CN1C(=O)CCC1c1cccnc1