RepSox

CAS : 446859-33-2

Ref. 3D-FR44793

Informations sur le produit

• Nom: RepSox
• Synonymes: ALK5 Inhibitor II, 1,5-Naphthyridine, 2-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]-, 1,5-naphthyridine, 2-[5-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]-, 2-[5-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl]-1,5-naphthyridine, Repsox
• CAS: 446859-33-2

Description

Selective inhibitor of the transforming growth factor beta receptor TGFβ1. RepSox can replace Sox, a transcriptional factor required for cell self-renewal, in reprogramming of adult cells to induced pluripotent stem cells (iPSCs). In the cloned interspecies embryos, RepSox induced expression of pluripotency regulatory genes Oct4 and Nanog, improved viability and developmental potential of embryos in the pre-implantation stage.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 287.32 g/mol
• Formule: C₁₇H₁₃N₅
• Degré de pureté: Min. 95%
• Couleur/Forme: Powder
• InChI: InChI=1S/C17H13N5/c1-11-4-2-5-16(20-11)17-12(10-19-22-17)13-7-8-14-15(21-13)6-3-9-18-14/h2-10H,1H3,(H,19,22)
• Code InChI: InChIKey=LBPKYPYHDKKRFS-UHFFFAOYSA-N
• SMILES: Cc1cccc(-c2[nH]ncc2-c2ccc3ncccc3n2)n1