Silybin

CAS : 22888-70-6

Ref. 3D-FS02332

Informations sur le produit

• Nom: Silybin
• Synonymes: Silibinin 2-[2R ,3R-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1 ,4-benzodioxin-6-yl]-2R,3R-dihydro-3,5,7-trihydroxy-4H-1-benzopyranone, (2R,3R)-2-[(2R,3R)-2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one, (2R,3R)-3,5,7-trihydroxy-2-[(2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydro-4H-chromen-4-one, (2R,3R)-3,5,7-trihydroxy-2-[(2S,3S)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydro-4H-chromen-4-one, 1,4-Benzodioxin, 4H-1-benzopyran-4-one deriv., 2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-6-(3,5,7-trihydroxy-4-oxobenzopyran-2-yl)benzodioxin, 4-Chromanone, 3,5,7-trihydroxy-2-[3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxan-6-yl]-, 4H-1-Benzopyran-4-one, 2-[(2R,3R)-2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-, (2R,3R)-, 4H-1-Benzopyran-4-one, 2-[2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-, [2R-[2α,3β,6(2R*,3R*)]]-, 7C3Mt, Mepasil, Milk Thistel P.E., Milk Thistle Extract, Realsil, Silibinin, Silibinin A, Silliver, Silybin A, Silybin b₁, Silybine, Silybum Extract, Silybum marianum, Silybum substance E₆, Silymarin Group, Silymarin I, Silymarin MZ 80, Silymarine I
• CAS: 22888-70-6

Description

Silybin is a natural compound derived from the plant milk thistle. It is an inhibitor of CDK2, which are cyclin-dependent kinases that regulate the cell cycle. This inhibition leads to apoptosis and has been shown to be effective against cancer cells in vitro and in vivo. Silybin also inhibits other CDKs such as CDK4 and CDK6, which have been shown to be related to tumorigenesis. Silybin has also been shown to inhibit protein synthesis in human cancer cells.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 482.44 g/mol
• Formule: C₂₅H₂₂O₁₀
• Degré de pureté: Min. 97 Area-%
• Couleur/Forme: Powder
• InChI: InChI=1S/C25H22O10/c1-32-17-6-11(2-4-14(17)28)24-20(10-26)33-16-5-3-12(7-18(16)34-24)25-23(31)22(30)21-15(29)8-13(27)9-19(21)35-25/h2-9,20,23-29,31H,10H2,1H3/t20?,23-,24?,25+/m0/s1
• Code InChI: InChIKey=SEBFKMXJBCUCAI-DBMPWETRSA-N
• SMILES: COc1cc(C2Oc3cc([C@H]4Oc5cc(O)cc(O)c5C(=O)[C@@H]4O)ccc3OC2CO)ccc1O