Sodium chlorodifluoroacetate

CAS : 1895-39-2

Ref. 3D-FS15452

Informations sur le produit

• Nom: Sodium chlorodifluoroacetate
• Synonymes: 2-Chloro-2,2-difluoroacetate, 2-Chloro-2,2-difluoroacetic acid sodium salt, Acetic acid, 2-chloro-2,2-difluoro-, sodium salt (1:1), Acetic acid, chlorodifluoro-, sodium salt, Sodium 2-chloro-2,2-difluoroacetate, Sodium difluorochloroacetate

Description

Sodium chlorodifluoroacetate (CFDA) is a potent inhibitor of the enzyme hydroxylase, which is an important step in the synthesis of epidermal growth factor. CFDA is a benzimidazole compound that is used as a control agent for human liver and rat liver microsomes. The reaction mechanism of CFDA involves the formation of a covalent bond between the hydroxyl group on CFDA and a cysteine residue on the enzyme, leading to inhibition. This inhibition prevents further production of epidermal growth factor and causes cell death by apoptosis. This drug has been shown to have transport properties, as it can cross the epidermis barrier in rats. Sodium chlorodifluoroacetate also inhibits malonic acid oxidation, which may be related to its effects on cancer cells.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 152.46 g/mol
• Formule: C₂ClF₂O₂·Na
• Degré de pureté: Min. 95%
• Couleur/Forme: White Powder