(S)-2-(5-(((3-Methyl-1-oxo-1,2-dihydrobenzo[f]quinazolin-9-yl)methyl)amino)-1-oxoisoindolin-2-yl)pentanedioic acid

CAS : 139987-54-5

Ref. 3D-FS175109

Informations sur le produit

• Nom: (S)-2-(5-(((3-Methyl-1-oxo-1,2-dihydrobenzo[f]quinazolin-9-yl)methyl)amino)-1-oxoisoindolin-2-yl)pentanedioic acid
• Synonymes: (2S)-2-(5-{[(3-methyl-1-oxo-1,4-dihydrobenzo[f]quinazolin-9-yl)methyl]amino}-1-oxo-1,3-dihydro-2H-isoindol-2-yl)pentanedioic acid, (2S)-2-[5-[[(1,2-Dihydro-3-methyl-1-oxobenzo[f]quinazolin-9-yl)methyl]amino]-1,3-dihydro-1-oxo-2H-isoindol-2-yl]pentanedioic acid, (2s)-2-(5-[[(3-Methyl-1-oxo-1,2-dihydrobenzo[f]quinazolin-9-yl)methyl]amino]-1-oxo-1,3-dihydro-2H-isoindol-2-yl)pentanedioic acid, (S)-2-(5(((1,2-Dihydro-3-methyl-1-oxobenzo[f]quinazolin-9-yl)methyl)amino)1-oxo-2-isoindolinyl)glutaric acid, (s)-2-(5-(((3-Methyl-1-oxo-1,2-dihydrobenzo[f]quinazolin-9-yl)methyl)amino)-1-oxoisoindolin-2-yl)pentanedioic acid, 1843U89, Benzo[f]quinazoline, pentanedioic acid deriv., Bw-1843U89, Gs-7904, Gw-1843, Gw-1843U89, Osi 7904L, Osi-7904, Pentanedioic acid, 2-[5-[[(1,2-dihydro-3-methyl-1-oxobenzo[f]quinazolin-9-yl)methyl]amino]-1,3-dihydro-1-oxo-2H-isoindol-2-yl]-, (2S)-, Pentanedioic acid, 2-[5-[[(1,2-dihydro-3-methyl-1-oxobenzo[f]quinazolin-9-yl)methyl]amino]-1,3-dihydro-1-oxo-2H-isoindol-2-yl]-, (S)-

Description

(S)-2-(5-(((3-Methyl-1-oxo-1,2-dihydrobenzo[f]quinazolin-9-yl)methyl)amino)-1-oxoisoindolin-2-yl)pentanedioic acid is a pyrimidine compound that inhibits the enzyme thymidylate synthase. This leads to inhibition of DNA synthesis and cell proliferation. (S)-2-(5-(((3-Methyl-1-oxo-1,2,-dihydrobenzo[f]quinazolin--9yl)methyl)amino)-1 -oxoisoindolin-2 -yl)pentanedioic acid has been shown to be effective against colorectal adenocarcinoma in animal models. The drug has minimal toxicity and can be activated by protonation in acidic environments. It also binds to monoclonal antibodies, which

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 500.5 g/mol
• Formule: C₂₇H₂₄N₄O₆
• Degré de pureté: Min. 95%