Senkyunolide I

CAS : 94596-28-8

Ref. 3D-FS73834

Informations sur le produit

• Nom: Senkyunolide I
• Synonymes: 1(3H)-Isobenzofuranone,3-butylidene-4,5,6,7-tetrahydro-6,7-dihydroxy-, (3Z,6R,7R)-rel-, 1(3H)-Isobenzofuranone,3-butylidene-4,5,6,7-tetrahydro-6,7-dihydroxy-, (3Z,6a,7b)-, rel-(3Z,6R,7R)-3-Butylidene-4,5,6,7-tetrahydro-6,7-dihydroxy-1(3H)-isobenzofuranone
• CAS: 94596-28-8

Description

Senkyunolide I is a natural product that has been identified as the major active constituent of Rhizoma Gastrodiae. It exhibits potent anti-inflammatory and anti-tumor activities. Senkyunolide I inhibits the activity of the enzyme glutathione reductase (GSH-px) and prevents mitochondrial membrane potential collapse by inhibiting ATPase activity and increasing intracellular calcium concentration. This compound also inhibits P-glycoprotein (Pgp) and exerts an antioxidant effect on neuronal cells, leading to apoptosis in vitro. Senkyunolide I has shown to be a potent inhibitor of tumor cell growth in vivo, with no toxicity effects observed in mice or rats.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 224.25 g/mol
• Formule: C₁₂H₁₆O₄
• Degré de pureté: Min. 95%