Sauchinone

CAS : 177931-17-8

Ref. 3D-FS73944

Informations sur le produit

• Nom: Sauchinone
• Synonymes: (5aR,7R,8S,8aR,14aS,14bR)-5a,6,7,8,8a,14b-Hexahydro-7,8-dimethyl-5H-benzo[kl]bis[1,3]dioxolo[4,5-b:4′,5′-g]xanthen-5-one, (5aR,7R,8S,8aR,14aS,14bR)-7,8-dimethyl-5a,6,7,8,8a,14b-hexahydro-5H-benzo[kl]bis[1,3]dioxolo[4,5-b:4',5'-g]xanthen-5-one, 5H-Benzo[kl]bis[1,3]dioxolo[4,5-b:4′,5′-g]xanthen-5-one, 5a,6,7,8,8a,14b-hexahydro-7,8-dimethyl-, (5aR,7R,8S,8aR,14aS,14bR)-, 5H-Benzo[kl]bis[1,3]dioxolo[4,5-b:4′,5′-g]xanthen-5-one, 5a,6,7,8,8a,14b-hexahydro-7,8-dimethyl-, (5aα,7α,8β,8aβ,14aS*,14bβ)-, 5H-benzo[kl][1,3]dioxolo[4,5-b]-1,3-dioxolo[4,5-g]xanthen-5-one, 5a,6,7,8,8a,14b-hexahydro-7,8-dimethyl-, (5aR,7R,8S,8aR,14aS,14bR)-

Description

Sauchinone is a natural compound that has shown to be effective in the treatment of bowel disease. This compound is an inhibitor of the toll-like receptor (TLR) and has shown to reduce inflammation and oxidative injury. Sauchinone has been found to increase the production of growth factor-β1, which may be useful for treating injuries such as burns or wounds. The matrix effect of sauchinone on cell culture was investigated using dextran sulfate, which is known to induce apoptosis in cells. Chromatographic analysis showed that sauchinone inhibited DNA binding activity and had an effect on dna binding activity. Molecular docking analysis showed that sauchinone binds with TLR4 and inhibits its signaling pathway, preventing aberrant reactions from occurring. Sauchinone also inhibits NF-κB activation by inhibiting nuclear translocation, thus suppressing inflammatory response.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 356.37 g/mol
• Formule: C₂₀H₂₀O₆
• Degré de pureté: Min. 95%
• Couleur/Forme: Powder