SAG hydrochloride

CAS : 2095432-58-7

Ref. 3D-FS76762

Informations sur le produit

• Nom: SAG hydrochloride
• Synonymes: 3-​Chloro-​N-​[trans-​4-​(methylamino)​cyclohexyl]​-​N-​[[3-​(4-​pyridinyl)​phenyl]​methyl]​-​benzo[b]​thiophene-​2-​carboxamide hyd rochloride
• Marque: Biosynth
• Description: Smoothened agonist and activator of the Hedgehog signalling pathway with EC50 of 3 nM. SAG binds to the Smoothened heptahelical bundle and antagonises effects of the Smoothened antagonist cyclopamine. In previous studies, SAG activated neurogenesis and neuronal survival in cell and animal models as well as improved cell differentiation of human induced pluripotent cells into the neuronal lineage.

Propriétés chimiques

• Masse moléculaire: 526.52 g/mol
• Formule: C₂₈H₂₈ClN₃OS•HCl
• Degré de pureté: Min. 95%
• Couleur/Forme: Powder