(-)-Tephrosin

CAS : 76-80-2

Ref. 3D-FT137972

Informations sur le produit

• Nom: (-)-Tephrosin
• Synonymes: 12-alpha-Hydroxydeguelin, (7aR,13aR)-13,13a-Dihydro-7a-hydroxy-9,10-dimethoxy-3,3-dimethyl-3H-bis[1]benzopyrano[3,4-b:6′,5′-e]pyran-7(7aH)-one, (7aR,13aR)-7a-hydroxy-9,10-dimethoxy-3,3-dimethyl-13,13a-dihydro-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7aH)-one, 3H-Bis(1)benzopyrano(3,4-b:6',5'-e)pyran-7(7aH)-one, 13,13a-dihydro-7a-hydroxy-9,10-dimethoxy-3,3-dimethyl-, (7aR,13aR)-, 3H-Bis(1)benzopyrano(3,4-b:6',5'-e)pyran-7(7aH)-one, 13,13a-dihydro-7a-hydroxy-9,10-dimethoxy-3,3-dimethyl-, (7aR-cis)-, 3H-Bis[1]benzopyrano[3,4-b:6′,5′-e]pyran-7(7aH)-one, 13,13a-dihydro-7a-hydroxy-9,10-dimethoxy-3,3-dimethyl-, (7aR,13aR)-, 3H-Bis[1]benzopyrano[3,4-b:6′,5′-e]pyran-7(7aH)-one, 13,13a-dihydro-7a-hydroxy-9,10-dimethoxy-3,3-dimethyl-, (7aR-cis)-, Ccris 7115, Deguelinol I, Hydroxydeguelin

Description

(-)-Tephrosin is a quinone with potent antitumor activity. It has been shown to inhibit the mitochondrial membrane potential, which is important for the production of ATP in cells. (-)-Tephrosin also inhibits signal pathways and transcriptional regulation, which are involved in cell proliferation and tumor growth. The mechanism of (-)-tephrosin's antitumor activity is not yet known, but it has been shown to be active against skin cancer cells and Hl-60 cells. This drug also has diagnostic properties as it can be used to detect changes in the mitochondrial membrane potential. (-)-Tephrosin is stable at pH levels between 3-4 and does not react with sodium carbonate or biological fluids such as serum or urine. In plant physiology, (-)-tephrosin has been shown to have toxic effects on plants by inhibiting photosynthesis.

• Marque: Biosynth

Propriétés chimiques

• Degré de pureté: Min. 95%