Triclabendazole-sulfone

CAS : 106791-37-1

Ref. 3D-FT170991

Informations sur le produit

• Nom: Triclabendazole-sulfone
• Synonymes: 1H-Benzimidazole,5-chloro-6-(2,3-dichlorophenoxy)-2-(methylsulfonyl)- (9CI), Cga 110753, Triclabendazole sulfone

Description

Triclabendazole-sulfone is an anthelmintic drug that belongs to the group of drugs that are used for the treatment of worm infestations in animals. It has a high affinity for ATP-binding cassette transporter proteins, which are involved in transporting molecules across cellular membranes. The molecule is also able to bind to an enzyme called carbonyl reductase, which is involved in the metabolism of xenobiotics. Triclabendazole-sulfone has been shown to be effective against cancer cells resistant to chemotherapy and it can be detected in urine samples collected from humans up to 24 hours after dosing. This drug was found to be absorbed well via oral administration and had a low volume of distribution (Vd) and rapid elimination half-life (t1/2).

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 391.66 g/mol
• Formule: C₁₄H₉Cl₃N₂O₃S
• Degré de pureté: Min. 95%
• InChI: InChI=1S/C14H9Cl3N2O3S/c1-23(20,21)14-18-9-5-8(16)12(6-10(9)19-14)22-11-4-2-3-7(15)13(11)17/h2-6H,1H3,(H,18,19)
• Code InChI: InChIKey=ZEIHWBIRYIXBSV-UHFFFAOYSA-N
• SMILES: CS(=O)(=O)c1nc2cc(Oc3cccc(Cl)c3Cl)c(Cl)cc2[nH]1