3,4,5,6-Tetrahydro-2-pyrimidinethiol

CAS : 2055-46-1

Ref. 3D-FT176103

Informations sur le produit

• Nom: 3,4,5,6-Tetrahydro-2-pyrimidinethiol
• Synonymes: 1,3-Diazinane-2-thione, 1,4,5,6-Tetrahydro-2-pyrimidinethiol, 2(1H)-Pyrimidinethione, tetrahydro-, 2-(1H)-Tetrahydropyrimidinethione, 2-Mercapto-1,4,5,6-tetrahydropyrimidine, 2-Mercapto-3,4,5,6-tetrahydropyrimidine, 2-Mercaptotetrahydropyrimidine, 3,4,5,6-Tetrahydro-1H-pyrimidine-2-thione, 3,4,5,6-Tetrahydro-2(1H)-pyrimidinethione, 3,4,5,6-Tetrahydro-2-mercaptopyrimidine, Cyclic propylene thiourea, Hexahydropyrimidine-2-thione, N,N′-Trimethylenethiourea, NSC 21316, Perhydropyrimidine-2-thione, Tetrahydro-2(1H)-pyrimidinethione, Tetrahydropyrimidine-2-thione, Thiourea, N,N′-1,3-propanediyl-, Trimethylenethiourea, tetrahydropyrimidine-2(1H)-thione

Description

3,4,5,6-Tetrahydro-2-pyrimidinethiol is a thione antibiotic that is resistant to many antibiotic-resistant strains. It is the most potent and selective inhibitor of matrix metalloproteinases (MMPs) that has been discovered so far. 3,4,5,6-Tetrahydro-2-pyrimidinethiol inhibits MMPs by binding to the active site of the enzyme and forms a covalent bond with the alpha carbon atom of a peptide bond in the active site. This prevents cleavage of the peptide bond and thereby prevents the degradation of collagen in extracellular matrices. 3,4,5,6-Tetrahydro-2-pyrimidinethiol has been detected in urine samples using an analytical method that employs electrochemical detection with a carbonyl group as a probe. This compound also has antihypertensive activity

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 116.19 g/mol
• Formule: C₄H₈N₂S
• Degré de pureté: Min. 95%
• InChI: InChI=1S/C4H8N2S/c7-4-5-2-1-3-6-4/h1-3H2,(H2,5,6,7)
• Code InChI: InChIKey=NVHNGVXBCWYLFA-UHFFFAOYSA-N
• SMILES: S=C1NCCCN1