Temocillin disodium

CAS : 61545-06-0

Ref. 3D-FT32659

Informations sur le produit

• Nom: Temocillin disodium
• Synonymes: 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((carboxy-3-thienylacetyl)amino)-6-methoxy-3,3-dimethyl-7-oxo-, disodium salt, (2S,5R,6S)-, 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((carboxy-3-thienylacetyl)amino)-6-methoxy-3,3-dimethyl-7-oxo-, disodium salt, (2S-(2alpha,5alpha,6alpha))-, 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[(carboxy-3-thienylacetyl)amino]-6-methoxy-3,3-dimethyl-7-oxo-, disodium salt, [2S-(2α,5α,6α)]-, 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[2-carboxy-2-(3-thienyl)acetyl]amino]-6-methoxy-3,3-dimethyl-7-oxo-, sodium salt (1:2), (2S,5R,6S)-, Antibiotic BRL 17421, Brl 17421, Disodium (2S-(2alpha,5alpha,6alpha))-6-(carboxylato-3-thienylacetamido)-6-methoxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate, Temocillin disodium salt

Description

Temocillin disodium is an aminoglycoside antibiotic that inhibits protein synthesis. Temocillin disodium is a prodrug that is hydrolyzed in vivo to temocillin, its active form. This product has been shown to inhibit the growth of certain bacterial strains, including Escherichia coli and Enterobacter cloacae. Temocillin disodium binds to the ribosomal 30S subunit and blocks the site for aminoacyl-tRNA binding, which prevents the formation of a functional translational complex and blocks protein synthesis. It also inhibits beta-lactamase activity by binding to bacterial cell wall penicillin-binding proteins, as well as inhibiting fatty acid biosynthesis by blocking acyl carrier protein (ACP) synthase, leading to cell death.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 458.42 g/mol
• Formule: C₁₆H₁₆N₂Na₂O₇S₂
• Degré de pureté: Min. 81 Area-%
• Couleur/Forme: White Powder