Informations sur le produit
Nom :
(24R)-24-Hydroxycalcitriol
Synonymes :
- 1-alpha,24(R),25-Trihydroxyvitamin D3(1-alpha,3-beta,5Z,7E,24R)-9,10-Secocholesta-5,7,10(19)-triene-1,3,24,25-tetrol
- (1R,3R,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,4R)-4,5-Dihydroxy-1,5-dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-cyclohexanediol
- (24R)-1a,24,25-Trihydroxyvitamin D3
- (24R)-1α,24,25-Trihydroxyvitamin D<sub>3</sub>
- 1a,24R,25-Trihydroxycholecalciferol
- 1a,24R,25-Trihydroxyvitamin D3
- 1α,24R,25-Trihydroxyvitamin D<sub>3</sub>
- 9,10-Secocholesta-5,7,10(19)-triene-1,3,24,25-tetrol, (1α,3β,5Z,7E,24R)-
- 9,10-Secocholesta-5,7,10(19)-triene-1,3,24,25-tetrol,(1a,3b,5Z,7E,24R)- (9CI)
- Pri 2193
- Voir d'autres synonymes
- Ro 21-7729
- 1,3-Cyclohexanediol, 5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,4R)-4,5-dihydroxy-1,5-dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-, (1R,3R,5Z)-
Description :
(24R)-24-Hydroxycalcitriol is a metabolite of vitamin D3. It is a form of vitamin D that is not biologically active and can be converted to calcitriol, the active form of the vitamin, by 24-hydroxylase. This process occurs in the liver and kidneys. (24R)-24-Hydroxycalcitriol has been shown to have minimal activity in animals, but has been shown to inhibit leukemic cells when it is given orally or expressed recombinantly in cultured cells. The effectiveness of this drug may be due to its ability to bind with toll-like receptor 2 on the surface of leukemia cells and activate them, which leads to cellular apoptosis.
Avis:
Nos produits sont destinés uniquement à un usage en laboratoire. Pour tout autre usage, veuillez nous contacter.
Marque:
Biosynth
Stockage à long terme :
Notes :
Propriétés chimiques
Masse moléculaire :
432.64 g/mol
Formule :
C27H44O4
Degré de pureté :
Min. 95%
Couleur/Forme :
Powder
MDL:
Point de fusion :
Point d'ébullition :
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Code SH :
