VE 822

CAS : 1232416-25-9

Ref. 3D-FV137734

Informations sur le produit

• Nom: VE 822
• Synonymes: 3-[3-[4-[(Methylamino)methyl]phenyl]-5-isoxazolyl]-5-[4-[(1-methylethyl)sulfonyl]phenyl]-2-pyrazinamine, Vx970, Ve-822

Description

VE 822 is a novel drug that has been shown to be effective against squamous carcinoma in vitro. VE 822 binds to the polymerase chain and inhibits its synthesis of RNA, halting cell growth and preventing the duplication of genetic information. This drug also has minimal toxicity in laboratory mice with solid tumours and does not show any signs of drug interactions. VE 822 may be able to inhibit radiation-induced tumorigenesis by preventing the formation of reactive oxygen species (ROS).

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 463.55 g/mol
• Formule: C₂₄H₂₅N₅O₃S
• Degré de pureté: Min. 98 Area-%
• Couleur/Forme: Powder
• InChI: InChI=1S/C24H25N5O3S/c1-15(2)33(30,31)19-10-8-18(9-11-19)21-14-27-24(25)23(28-21)22-12-20(29-32-22)17-6-4-16(5-7-17)13-26-3/h4-12,14-15,26H,13H2,1-3H3,(H2,25,27)
• Code InChI: InChIKey=JZCWLJDSIRUGIN-UHFFFAOYSA-N
• SMILES: CNCc1ccc(-c2cc(-c3nc(-c4ccc(S(=O)(=O)C(C)C)cc4)cnc3N)on2)cc1