Informations sur le produit
- 3-Phorbinepropanoic acid, 9-ethenyl-14-ethyl-4,8,13,18-tetramethyl-20-oxo-, methyl ester, (3S,4S)-
- Pyrophaeophorbide-a-monomethyl ester
- Methyl 4-(9-Ethenyl-14-Ethyl-4,8,13-Trimethyl-20-Oxophorbin-3-Yl)Butanoate
- Methyl 3-(9-Ethenyl-14-Ethyl-4,8,13,18-Tetramethyl-20-Oxo-24,25-Dihydrophorbin-3-Yl)Propanoate
- Methyl pyropheophorbide-a
Pyropheophorbide a methyl ester is an organic compound that is used in photodynamic therapy. It binds to hemoglobin, which is the oxygen-carrying protein of red blood cells. The binding of pyropheophorbide a methyl ester to hemoglobin causes it to become unstable and break down into reactive molecules that are cytotoxic. The carbonyl group on this molecule also makes it a good substrate for ABCG2, which is a transporter protein found on the surface of cancer cells. This drug has shown success in treating prostate cancer cells and herpes simplex virus. Pyropheophorbide a methyl ester has been shown to produce tumour necrosis when irradiated with UVB light, by inducing apoptosis and inducing the production of reactive oxygen species.
Propriétés chimiques
Question d’ordre technique sur : 3D-GAA45367 Pyropheophorbide a methyl ester
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