1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one

CAS : 6969-71-7

Ref. 3D-GAA96971

Informations sur le produit

• Nom: 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one
• Synonymes: 1,2,4-Triazolo-[4,3-a]-Pyridine-3(2H)-One, 1,2,4-triazolo-4,3-pyridin-3(2H)-one, 1,2,4-trizolo(4,3a)pyridin-3(2H)-one, 2H,3H-[1,2,4]Triazolo[4,3-a]pyridin-3-one, 2H-[1,2,4]Triazolo[4,3-a]pyridin-3-one, 3-Hydroxytriazolo[4,3-a]pyridine, NSC 68462, [1,2,4]Triazolo[4,3-a]pyridin-3-ol, s-Triazolo[4,3-a]pyridin-3-ol

Description

1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one is a potent inhibitor of the enzyme c-glycosylase. This compound has been used in pharmaceutical preparations and as a feedstock in organic syntheses. It is used to produce the anti-inflammatory drug piroxicam, which inhibits the action of cyclooxygenase and blocks the synthesis of prostaglandins. 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one also has been shown to inhibit crystallization of the bovine liver enzyme phosphatidylcholine:cholesterol acyltransferase (PCAT). The inhibition was found to be competitive with respect to PCAT substrate and was not due to inhibition of PCAT by 1,2,4-triazolo[4,3-a]pyridin-3(

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 135.13 g/mol
• Formule: C₆H₅N₃O
• Degré de pureté: Min. 95%